@article{oai:hirosakiuhw.repo.nii.ac.jp:00000184,
 author = {Nagaki, Masahiko and Goto, Yoshifumi and Horiba, Takashi and Yamanouchi, Kanako and Tsujiguchi, Takakiyo and Chounan, Yukiyasu},
 issue = {1},
 journal = {弘前医療福祉大学紀要},
 month = {Mar},
 note = {Article, We obtained essential oil from wood chips of the Aomori hiba tree by steam distillation. Component analysis of the essential oil and extract of distilled water identified 25 kinds of components, equivalent to 75% of the total amount of essential oil. The main component was thujopsene 35.6%, followed by epi-cedrol 15.9%.
 In addition, 32 ingredients were identified from a distilled water extract of these wood chips. The main component was epi-cedrol 16.1%, followed by terpinen-4-ol 14.8% and thujopsene 10.3%.
 Among other constituents, hinokitiol showed antimicrobial activity against all bacteria tested, namely Escherichia coli, EHEC (enterohemorrhagic E. coli), Pseudomonas aeruginosa, Candida albicans, and MRSA (methicillin-resistant Staphylococcus aureus), while cedrol showed activity against all but P. aeruginosa. While an aged sample of essential oil did not show antimicrobial activity, a newly obtained sample showed activity against Gram-positive bacteria (S. aureus, MRSA) and Gramnegative bacteria E. coli, Shigella sonnei)
 私たちは、青森ヒバの木材チップの水蒸気蒸留を行い、精油を得た。さらに蒸留湯はヘキサン抽出を行った。精油から25種類の化合物を同定したが、主要成分はthujopsene（36.5%）、次いでepi-cedrol（15.9%）と続いた。更に、蒸留湯抽出物から32 種類の成分を同定した。主成分はepi-cedrolが多く16.1%、続いてterpinen-4-olが14.8%、thujopseneが10.3%であった。
 更に、私たちは精油と2、3の成分について抗菌活性試験を行った。Hinokitiolは、使用したすべての菌（大腸菌、腸管出血性大腸菌、緑膿菌、MRSA、および真菌のカンジダアルビカンス）で強い活性がみられた。cedrolでも緑膿菌以外は活性を示した。ヒバチップの精油では、グラム陽性菌（黄色ブドウ球菌、MRSA）およびグラム陰性菌（大腸菌、赤痢菌）に活性を示した。},
 pages = {15--21},
 title = {Phytoconstituent profile and biological activity of wood chips of Aomori Hiba (Thujopsis dolabrata SIEB. et ZUCC. var. hondai MAKINO)},
 volume = {10},
 year = {2019}
}